Geelong has made two changes for their Round 2 AFLW clash against Collingwood at Victoria Park on Saturday.

The Cats will be looking to respond with an improved performance against the Pies after an opening round defeat against North Melbourne.

It will be a big occasion for recent draftees Stephanie Williams and Olivia Barber who have been named to make their AFLW debuts.

Williams is an exciting forward who plays much taller than her 162cm frame, boasting explosive speed and a high leap.

The 19-year-old was selected with pick 27 in last year's draft after making her way to Geelong via the Darwin Buffaloes and Geelong Falcons.

A former basketballer who made the switch to footy, Barber impressed in her bottom-age under-18 national championships campaign, named as All-Australian full forward.

Also capable of playing in the ruck, the former Murray Bushranger has been named to start in attack alongside Williams.

Barber and Williams replace defender Millie Brown (injured) and ruck Rene Caris (omitted).

The game will also be a big occasion for for Aasta O'Connor who will play her 25th AFLW game.

It will be Aasta's 13th game as a Cat after previously spending two years at the Western Bulldogs where she played 12 games and was a member of their 2018 premiership team.

Gates will open at Victoria Park on Saturday from 1.40pm AEDT with the first bounce at 3.10pm AEDT.

AFLW Round 2 Team

In: Stephanie Williams, Olivia Barber
Out: Mille Brown (injured), Rene Caris